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KMID : 0811820120160010001
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Journal of Korean Society of Pediatric Nephrology
2012 Volume.16 No. 1 p.1 ~ p.8
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Circadian Rhythm of ADH, Hypercalciuria, and Solute Diuresis as Pathogenesis of Enuresis
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Kang Hee-Gyung
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Abstract
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Nocturnal polyuria is one of the main pathogenic mechanisms of enuresis. Disturbance of circadian rhythm of antidiuretic hormone (ADH or AVP), hypercalciuria, and/or solute diuresis are considered to cause nocturnal polyuria, which in turn causes enuresis in patients with relatively small bladder capacity and high threshold for awakening. Evaluation of these factors would guide the therapeutic approach for enuresis.
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KEYWORD
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Enuresis, Nocturnal polyuria, Circadian rhythm, Antidiuretic hormone, Solute diuresis
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